The Pakistani rupee strengthened against the US dollar, appreciating 0.04% during the opening minutes of trading in the inter-bank market on Monday. At 10am, the local currency was hovering at 280.05, a gain of Re0.12 against the greenback. During the previous week, the Pakistan rupee posted a marginal gain as it appreciated by Re0.08 or 0.03% against the US dollar in the inter-bank market.